The first report of pregnancies following blastocyst automated vitrification in Europe

Abstract
Embryo cryopreservation is a valuable technique in assisted reproductive technology (ART) that increases cumulative pregnancy rates and allows postponement of embryo transfer in patients with undesirable uterine or clinical conditions. Although vitrification has been considered the most efficient method to freeze oocytes and embryos, it is time-consuming and highly operator-dependent. Gavi® is the first semi-automated machine for vitrification capable of controlling crucial variables such as temperature, volume, concentration and exposure time during the vitrification process. We report the first two pregnancies obtained with blastocysts cryopreserved with the Gavi® semi-automated vitrification system in Europe. These outcomes suggest that the utilization of semi-automated vitrification may contribute to improve the outcomes and laboratory logistics of fertility clinics.

Autori: Mariabeatrice Dal Canto, Clarissa Moutier, Fausta Brambillasca, Maria Cristina Guglielmo, Alessandro Bartolacci, Rubens Fadini, Mario Mignini Renzini, Jose Buratini